Coronaviruses and Central Nervous System Manifestations

Coronaviruses and Central Nervous System Manifestations

Blog Article

SARS-CoV-2 is a highly pathogenic coronavirus that has caused an ongoing worldwide pandemic.Emerging in Wuhan, China Cologne in December 2019, the virus has spread rapidly around the world.Corona virus disease 2019 (COVID-19), which is caused by SARS-CoV-2, has resulted in significant morbidity and mortality.The most prominent symptoms of SARS-CoV-2 infection are respiratory.

However, accumulating evidence highlights involvement of the central nervous system (CNS).This includes headache, anosmia, meningoencephalitis, acute ischemic stroke, and several presumably Thread Aids post/para-infectious syndromes and altered mental status not explained by respiratory etiologies.Interestingly, previous studies in animal models emphasized the neurotropism of coronaviruses; thus, these CNS manifestations of COVID-19 are not surprising.This minireview scans the literature regarding the involvement of the CNS in coronavirus infections in general, and in regard to the recent SARS-CoV-2, specifically.